New gene map reveals cancer’s Achilles’ heel

Team of researchers switches off almost 18,000 genes
Jovana Drinjakovic

Scientists have mapped out the genes that keep our cells alive, creating a long-awaited foothold for understanding how our genome works and which genes are crucial in disease like cancer.

A team of Toronto researchers, led by Professor Jason Moffat from the University of Toronto’s Donnelly Centre, with a contribution from Stephane Angers from the Faculty of Pharmacy, have switched off, one by one, almost 18,000 genes, 90 per cent of the entire human genome, to find the genes that are essential for cell survival.

A tumour you can unroll: engineers create new technology for understanding cancer growth

“It’s simple enough that one could teach an undergrad to do it in a week,” professor says
Tyler Irving

A team of U of T engineers is unrolling the mysteries of cancer – literally. They have developed a way to grow cancer cells in the form of a rolled-up sheet that mimics the 3D environment of a tumour, yet can also be taken apart in seconds.

The platform, described in a new Nature Materials paper, offers a way to speed up the development of new drugs and therapies and ask new questions about how cancer cells behave.

Northern exposure: how this anthropology professor is changing health care in Nunavut

UTM's Tracey Galloway
Blake Eligh

In a career that has taken her from an urban intensive care ward to the farthest reaches of Canada, Assistant Professor Tracey Galloway is helping to change the delivery of health care in Canada’s icy north.  

These U of T faculty are now fellows of the American Association for the Advancement of Science

AAAS welcomes leading researchers Cheryl Arrowsmith and Greg Evans
Carolyn Morris and Tyler Irving

Two U of T faculty members are among the latest fellows of the American Association for the Advancement of Science (AAAS).

Professor Greg Evans of chemical engineering was recognized for his important contributions to air pollution research and his leadership in engineering education.

Professor Cheryl Arrowsmith of medical biophysics was honoured for enabling the research community to benefit from open-access science, speeding up the discovery of new therapies.

The prestigious honour was announced on Nov. 23.

Building a better heart: celebrating the first year of the Ted Rogers Centre for Heart Research

Heidi Singer

What if we could identify the gene responsible for a baby’s heart defect, grow a piece of her heart on a chip, then test drugs to find the one able to shut down the defective gene?

SeamlessMD raises $1.1 million from angel investors, BDC Capital, Funders Club

Company co-founded by alumnus Joshua Liu is making a difference to surgery patients and providers
Erin Howe

The next time you’re scheduled for surgery, your to-do list could include accessing a web-based program or downloading an app to your smartphone or tablet – thanks to a recent U of T grad and a startup with serious backers.

SeamlessMD, a company co-founded by alumnus Dr. Joshua Liu, is helping people prepare for and recover from surgery using their mobile devices and home computers.

Online chat with YouTube star and medical expert Dr. Mike Evans

Krisha Ravikantharaja

Family physician and University of Toronto associate professor by day. YouTube celebrity by night. And now you have the chance to chat with him live.

U of T Medicine is partnering with the Toronto Star for a live web chat with Dr. Michael Evans, scheduled for noon on Thursday, Nov. 19. The focus of the chat is weight control, and organizers say they’re hoping for an open discussion where people will share the strategies that work for them.

Why most cancer deaths occur in middle-income and low-income countries

Researcher outlines cost-effective strategies to prevent and treat cancer
Nicole Bodnar

New research shows investments in the prevention, detection, diagnosis and treatment of cancer – as well as palliative care – are increasingly needed in the countries where most of the world's cancer deaths occur: low-income and middle-income countries.

Convocation 2015: meet honorary grad Sir Richard Peto

Sir Richard Peto, FRS is professor of medical statistics and epidemiology at the University of Oxford, and co-director (with Professor Sir Rory Collins) of the Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU).

He was made a Fellow of the Royal Society of London in 1989 for introducing meta-analyses of randomised trials, was knighted by Queen Elizabeth in 1999 for services to epidemiology, and received in 2010 and 2011 the Cancer Research UK and the BMJ Lifetime Achievement Award.

Remembering the veterans of Sunnybrook: a Convocation 2015 story

“I got to bear witness to the end of a generation that experienced this unfathomable horror,” says former firefighter who graduates today
Heidi Singer

Black-and-white photos taped to hospital doors show healthy, strong young men in uniform, on their way to fight the Nazis.

Then, because they were the lucky ones, the men appear as smiling young grooms and proud fathers — and as gray-scale turned to colour, beaming grandfathers.  

University of Toronto physical therapy student Danny Slack spent five weeks interning at Sunnybrook Veterans Centre last year. He expected to help the residents, many in their late 90s, improve their mobility and manage their pain.

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